منابع مشابه
G-proteins
Animals have evolved multiple strategies for coping with the presence of pathogenic microbes. The best characterized is the immune response where animals activate their physical and cellular defenses to respond to invading microorganisms. However, behavioral changes can also be triggered by exposure to microbes and play an important role in defending many species, including humans, from pathoge...
متن کاملG proteins and phototransduction.
Phototransduction is the process by which a photon of light captured by a molecule of visual pigment generates an electrical response in a photoreceptor cell. Vertebrate rod phototransduction is one of the best-studied G protein signaling pathways. In this pathway the photoreceptor-specific G protein, transducin, mediates between the visual pigment, rhodopsin, and the effector enzyme, cGMP phos...
متن کاملG proteins find partners
G proteins find partners n recent years, scientists have identified many complexes containing most or all of the components needed to mount a particular signaling cascade. In contrast, Peter Hein, Moritz Bünemann (University of Würzburg, Germany), and colleagues find that a G protein signaling pathway works just as well, if not better, when receptor and G protein start out apart. Several groups...
متن کاملG-proteins for spindle geometry
kinetochore protein plays both sides of the checkpoint field, according to Weaver et al. on page 551. They show that CENP-E, a mitotic checkpoint-silencing protein, also stimulates the amount of checkpoint inhibitor released from an unattached kinetochore. The mitotic checkpoint is the major mechanism preventing chromosomal loss during mammalian mitosis. Unattached kinetochores generate an inhi...
متن کاملNatural polyamines stimulate G-proteins.
The natural polyamines spermine and spermidine, the biosynthetic precursor putrescine and their analogues cadaverine and tyramine stimulate the GTPase activity of purified GTP-binding proteins (Go/Gi) from calf brain reconstituted into phospholipid vesicles. The order of potency was spermine greater than spermidine greater than putrescine = cadaverine greater than tyramine. The physiological re...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2007
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000266971.15127.e8